苯偶酰通過苯基重排得到二苯基乙醇酸的反應(yīng)。
反應(yīng)機理
最后酸的脫氫是此反應(yīng)進行主要驅(qū)動力。
反應(yīng)實例
參考文獻
Liebig, J. Ann. 1838, 27. Justus von Liebig (1803-1873) pursued his Ph.D. in organic chemistry in Paris under the tutelage of Joseph Louis Gay-Lussac (1778-1850). He was appointed the Chair of Chemistry at Giessen University, which incited a furious jealousy amongst several of the professors already working there because he was so young. Fortunately, time would prove the choice was a wise one for the department. Liebig would soon transform Giessen from a sleepy university to the Mecca of organic chemistry in Europe. Liebig is now considered the father of organic chemistry. Many classic name reactions were published in the journal that still bears his name, Justus Liebigs Annalen der Chemie.2
尤斯圖斯·馮·李比希 (1803-1873)在吉森大學(xué)變?yōu)槿珰W知名大學(xué)。現(xiàn)在李比希被尊為有機化學(xué)之父。許多期刊上發(fā)表的經(jīng)典人名反應(yīng)都以他的名字命名，如期刊也以他命名（ Justus Liebigs Annalen der Chemie）。
2. Zinin, N. Justus Liebigs Ann. Chem. 1839, 31, 329.
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6. Patra, A.; Ghorai, S. K.; De, S. R.; Mal, D. synthesis 2006, 15, 2556-2562.
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8. Askin, D.; Reamer, R. A.; Jones, T. K.; Volante, R. P.; Shinkai, I. Tetrahedron Lett.1989, 30, 671.
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編譯自：Name Reactions （A Collection of Detailed Reaction Mechanisms）, Jie Jack Li, Benzilic acid rearrangement，page 45-46.
